Infrex FRM - Functional Restoration Machine


The Infrex FRM is indicated for rehabilitation, pain control, soft and hard tissue accelerated healing. 

   The below article from explains how a new electropulse therapy may be producing holes in actual tumors resulting in the death of the cancerous tumor cells.   The process, IRE - Irreversible electroporation operates on a principle of opening the cancer cell membrane by using higher intensity and greater pulse width duration of the electrical charge which results in keeping open molecules, inside the cancer cells, and death results.   The process is invasive and the application electrode is inserted inside the body.  

   According to the work of Dr. Albert Szent-Gyorgi, Nobel Prize Medicine 1937 for Szent-Gyorgi/Krebs Citric Acid Cycle, any "opening" from a submolecular level is the supplementing of excess electrons into the molecules, which are collections of atoms with stable and unstable electron rings around the nucleus.   The flow or feeding of electrons disrupts cycles of growth, especially in cancer cells which are growing unnaturally and rapidly.   The growth process of the cancer cells exposes them to the constant rearrangment of electrons in the shells surrounding the nucleus and this may be what is atomically known as "keeping open the molecule".  Because many healthy tissues in the body are not in some super growth state the effects are only on rapid growth cells, not healthy normal cells. 

   The below article is a new technique intended to be used in high risk areas where cancer resides and other therapies pose additional risk to the patient with conventional treatments.   The use of high frequency interferential type currents do  decrease external resistances which should result in the lack of need for physical surgery and internal intervention.  By decreasing resistances the current can now be directed to the actual targeted cancer cells.  More work needs to be done in this area but with the introduction of the Infrex FRM we feel the instrument is here that can target the cancer cells. 



Cancer treatment that PUNCHES HOLES in tumours could be latest weapon in war against disease

  • New treatment uses millions of electric pulses per second to make holes in cancer cells and kill them
  • Therapy does not damage surrounding healthy tissue
  • Now experts want to carry out larger clinical trials 


A minimally invasive cancer treatment that punches microscopic holes in tumours - without harming surrounding healthy tissue - could be the latest weapon in the war against cancer.

Irreversible electroporation (IRE) uses millions of electrical pulses per second to kill cancer cells but spare nearby tissue.

‘IRE may be especially beneficial in treating liver, lung, pancreatic and other cancers that are close to blood vessels, nerves and other sensitive structures,’ said the researchers who conducted the study.

New hope: IRE uses electric pulses to kills tumours at a cellular level

New hope: IRE uses electric pulses to kills tumours at a cellular level


  Treatment of cancers near sensitive sites usually involves surgery and a technique known as thermoablation, which heats and then freezes the tumour. 

But this can damage healthy tissue, posing a risk to nearby major blood vessels, nerves, ducts and other vital structures.

The study involved 25 patients who suffered with cancer that had spread to various parts of their body. The average size of the tumour was two centimeters.




IRE was used due to the location of the lesions – all were near vulnerable sites that would be affected by thermoablation. 

Dr Constantinos Sofocleous, an interventional radiologist at Memorial Sloan-Kettering Cancer Center in New York, completed all 30 treatment sessions with no major complications, showing IRE to be safe enough for further investigation in larger clinical trials. 

Until now, the main method of removing tumours that had spread was by surgery and thermoablation

Until now, the main method of removing tumours that had spread was by surgery and thermoablation

He presented his findings at the Society of Interventional Radiology's 38th Annual Scientific Meeting in New Orleans. 

He said: ‘The treatment appears to be especially beneficial in people with cancer that has spread and who do not have good treatment options.'

IRE involves making an incision the size of a pencil tip and feeding a tiny instrument to target the tumours. 

Strong electric fields are then generated to create tiny holes in the cancer cell membranes.

This kills them by disrupting the balance of molecules inside and outside the cell. 

Because IRE does not generate heat or cold, it stops surrounding cells becoming damaged. 

This makes IRE ideal for treating tumors close to tissues that are vulnerable to damage.

By increasing the strength, and duration of the electric pulses, the pores in the cancer cells remain open permanently. 

This causes microscopic damage to the cells, and they die.

The combination of minimally invasive surgery and IRE allows for faster recovery with less tissue injury, and it is hoped, a better long-term outcome than with traditional surgery. 

At a minimum, said Dr Sofocleous, the treatment offers the the patient an improved quality of life.

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This is a list of diagnosis that Medicare does not cover for the cost of a tens machine as of July 19, 2013 ( subject to change without notice). 

   For you to get a tens unit in the United States and have Medicare purchase it, you will need to get a prescription from your doctor (must be an MD, not PA or nurse practitioner) that is not related to back pain. Medicare has changed its policy and will not cover a tens units for several diagnoses. Once we get the doctor’s prescription along with your basic information, we can ship the unit to you. You will then need to re-visit your doctor after 31 days but before sixty days for a re-evaluation and the doctor must complete a Certificate of Medical Necessity and return it to us. Once the unit is purchased by Medicare, at the present time, they will cover two supplies per month.  The supplies can be topical pain lotions, skin creams, tens electrodes, tens cables, and those products ( no drugs ) related to relieving your chronic pain.   Most of the topicals are Tiger Balm patches & lotions, BioFreeze, hot/cold packs, Flex-all, and Vit. E/Aloe lotions.  

Please call (800-937-3993) or This email address is being protected from spambots. You need JavaScript enabled to view it.if we can be of additional service.


The diagnoses that Medicare will not cover are listed below:


          353.4       Lumbosacral root lesions, not elsewhere classified

·         720.2       Sacroiliitis, not elsewhere classified

·         721.3       Lumbosacral spondylosis without myelopathy

·         721.42     Thoracic or lumbar spondylosis with myelopathy – lumbar region

·         722.10     Lumbar intervertebral disc without myelopathy

·         722.52     Lumbosacral intervertebral disc

·         722.73     Intervertebral disc disorder myelopathy – lumbar region

·         722.83     Post laminectomy syndrome – lumbar region

·         722.93     Other and unspecified disc disorders, lumbar region

·         724.02     Spinal stenosis, lumbar region without neurogenic claudication

·         724.03     Spinal stenosis, lumbar region with neurogenic claudication

·         724.2       Lumbago

·         724.3       Sciatica

·         724.4       Thoracic or lumbosacral neuritis or radiculitis, unspecified, radicular syndrome of lower extremities

·         738.4       Acquired spondylolysthesis

·         739.3       Non-allopathetic lesions NEC (not elsewhere classified)-lumbar region

·         756.11     Spondylosysis, lumbosacral region

·         756.12     Spondylolisthesis

·         805.4       Fracture of vertebral column without mention of spinal cord injury,lumbar,closed

·         806.4       Fracture of vertebral column with mention of spinal cord injury, lumbar, closed

·         846.0       Sprains and strains of sacroiliac region – lumbosacral (joint) (ligament)

·         846.1       Sprains and strains of sacroiliac ligament

·         847.2       Sprains and strains of other and unspecified parts of back, lumbar

·         953.2       Injury to nerve roots and spinal plexus, lumbar root

·         339.0       346.9     784.0  Headaches    

·         524.6       TMJ (Temporomandibular pain)

·          625.9      Pelvic Pain

789.0      Visceral abdominal pain



When To Use Hot Or Cold Therapy

   It can really get confusing when one has a muscle strain, sprained ankle and other similar maladies and is told to use "cold therapy" and "heat therapy".   The mantras are "only use cold", "use cold for first 24-48 hours", "don't use cold use warm moist heat to stop your pain".    How is one to know what to do?   Well let's examine what to use but more importantly why to use the hot or cold therapy. 

   Generally speaking immediately following acute injury the body goes into what is called an "inflammatory response" and the area gets red, gets hot and swells.   During this time you don't want to inflame an inflammatory reaction and make it worse so the general rule is use cold therapy (cryotherapy).   The cold actually:

  • reduces the edema,
  • lessens the pain,
  • cools the temperature of the injured area, and
  • stops the inflammatory response.  

The inflammatory response is natural and helpful but it can cause more injury especially in cases such as spinal cord damage, or brain injury where the swelling causes additional injury to healthy tissues. 

   After the swelling has stopped, the pain subsided some, and the area cooled down, then warm, moist heat is indicated ( not dry heat ) and that occurs generally when a patient is trying to regain motion, function, movement yet, due to damaged tissues, range of motion is restricted.   As the patient tries to regain full range pain inhibits it and it is now that heat helps:

  • reduce pain
  • increase blood flow for faster healing
  • helps extend range of motion when used complemetary with exercise

   Now here's the "sleight of hand" that is often confusing to injured patients.  Each time a patient goes through an exercise routine then new/old tissues are actually reinjured.  That in and of itself re-excites the body's inflammatory response so in essence the patient now has a "new injury" brought on by the rehabilitation process.   So immediately after exercising it's best to use cold therapy, not warm moist, as the area being exercised is now in a new "acute" injury process.

  Using the Infrex FRM or Infrex Plus machines it's important,  in order to understand how we enhance recovery and/or improve athletic performance, to understand what are valence electrodes.   It is these electrodes we affect to accelerate recovery from injury and also to possibly enhance total overall health by reducing the free radicals found in our body.  It is also the increased quantity of free radicals produced by exercising that we want to minimize to protect overall long term health.   The process of exercising produces more free radicals.  It's that production and the destruction free radicals cause  that possibly leads to the danger of the "weekend warrior" injuries and health deteoriation.



This video, by Tyler DeWitt, is a very good example of what is a valence electrode and how it fits in the periodic table.  




   Below is a list of non covered diagnosis, and diagnosis codes,  by Medicare for the rental and purchase of a tens machine ( transcutaneous electrical nerve stimulator) , and the purchase of tens supplies.  MedFaxx is an accrediated provider of tens machines for Medicare patients, FOR NOW.




Functional Electrical Stimulation In Multiple Sclerosis


  The below article is a very good  summary article written by J. M. Campbell, Ph.D, P.T. explaining some of the electrical stimulation results for multiple sclerosis patients.  

    For clarity purposes the term "ES" or "Estim" is a generic declaration of an external device in most cases, that produces a flow of electrons from one electrode to the other of the same channel. The flow of the electrons produces an ionic reaction in the body in the areas between the electrodes, in most cases motor nerves and muscle tissue.  The most common use of a specific form of ES with multiple sclerosis patients is the term "Functional Electrical Stimulation", or FES.   This is a form of estim where one stimulates motor nerves, at the same time as attempting to move mentally.   The breaching of the gap between movement and the brain's message to move is preserved or restored.  The FES process is accomplished with voluntary repeated movement assisted by functional stimulation.  

   A quicker method of accomplishing functional electrical stimulation would be to use "medium frequency Infrex interferential stimulation" with volitional movement at the same time.   Typical FES applications involve multiple daily sessions ( 5 - 15), for 10 - 20 minutes whereas "functional stimulation" protocols are 1- 2x daily for 15 minutes at maximum output.   Functional stimulation is designed to also increase muscle bulk and strength.

  The reference to "healing decubitus ulcers" ( bed sores ) is generally a form of estim known as "pulsed galvanic stimulation", or "high voltage".

   The "reduce spasticity" can be accomplished by using FES to fatigue the muscle(s) however most studies fail to then continue to use estim for extended time periods to avoid future spasticity.   This accomplished by "interferential therapy" over night for 6 - 12 hours either sensory or subsensory.   The process of constant, low amperage stimulation of muscles stops spasticity.   Spasticity should be prevented, not treated.



Costochondritis or Chest Wall Pain

  Often chest pain is associated with heart attacks but costochondritis, or Tietze's syndrome, can be successfuly treated with medium frequency interferential therapy provided by the Infrex Plus.   The process of inflammation of the costal cartilage can result in pain and the negative charge of the Infrex helps reduce the inflammation while reducing or eliminating the pain.

   Specific protocols are provided for self treatment using interferential therapy at home.  The goal is to eliminate the source of the costochrondritis pain.



The definition from Wikipedia:

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